cell-biology

2 posts

What does Greatwall Kinase do in leukaemia cells?

Our new EMBO Reports paper with the Cutillas lab shows that AML cells need Greatwall kinase for cytokinesis, but its not responsible for ENSA phosphorylation in these cells. This is an interesting example how cellcycle control is reqired in different cell types, and could provide new therapeutic opportunities to target AML in the clinic